Diigo Links

Flap’s Smiles and Health Headlines: November 3, 2011

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These are my links for November 3rd from 15:40 to 15:45:

  • Thousands of lives could be saved if rest of UK adopted average diet in England, study concludes-“Around 4,000 deaths could be prevented every year if the UK population adopted the average diet eaten in England, concludes research published in BMJ Open.”

    Death rates for cardiovascular disease and cancer are higher in Scotland, Wales, and Northern Ireland than they are in England, and it is well known that these diseases are associated with a poor diet that is high in saturated fats and salt and low in fibre, fruits and vegetables.

    The researchers therefore looked at mortality data for coronary heart disease, stroke, and 10 cancers associated with diet, including those of the gullet, bowel, and stomach, in all four UK countries for the years 2007 to 2009 inclusive.

    And they estimated average intake of 10 dietary components, including energy intake, in each of the four countries, drawn from national representative data from the Family Food Survey for the same period.

    These data showed that people in Scotland and Northern Ireland consistently ate more saturated fat and salt and fewer fruits and vegetables every day than their English cousins, while the differences between Wales and England were less consistent over the three years.

    The authors then calculated what differences in death rates could be expected from population changes in average dietary quality, using the DIETRON model — a conceptual mathematical model that calculates the impact of food consumption on health outcomes.

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  • Pete Rose Sued By Dentist — He Charlie Hustled Me!!-“Baseball won’t have him back … and now, Pete Rose’s dentist is pissed at him too … claiming the MLB legend has refused to pay for almost $3k in dental services.

    Dr. Armen Terteryan is drillin’ Rose for $2,915.00 for “dental services rendered and not paid for” back in 2010.

    According to the lawsuit, filed in small claims court in L.A., the doc claims Rose agreed to the fees before “starting treatment” … though it’s unclear which procedures were performed on the baseball star.

    A small claims showdown has been scheduled for December 14th.”

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  • Overweight Teens Don’t Seem to Grasp Weight Loss Rules –-“Obese teens who want to lose weight may not be going about it in the most healthy or effective ways, according to new research.

    Simply put, the researchers said, teens trying to drop the pounds don’t seem to fully understand the link between exercise and calories. The analysis of nearly 44,000 adolescents who participated in the Philadelphia Youth Risk Behavioral Survey showed that, among the obese, girls who exercised still drank soda and boys didn’t exercise at all.

    In addition, three-quarters of the obese teens said they were trying to lose weight, but these were also the teens more likely to smoke, possibly as a weight loss aid, the study suggested.

    U.S. childhood obesity rates have tripled over the past three decades, and nearly one in three children in America is overweight or obese today. The new study, slated for presentation at the American Public Health Association’s annual meeting in Washington, D.C., sheds some light on why reducing these rates is such an uphill battle.”

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  • NYU team gets $2.2M grant to ID caries-causing bacteria-“A New York University (NYU) dental research team has received a four-year, $2.2 million grant from the National Institute of Dental and Craniofacial Research to use whole genome sequencing to identify the strains of lactobacilli bacteria that contribute to the development of severe early childhood caries.

    Severe early childhood caries can destroy most of a child’s teeth by age 3 and disproportionately affects underserved populations, including American Indians and Alaskan natives, NYU stated in a press release. Although the link between lactobacilli bacteria and severe early childhood caries has been known for almost a century, progress in delineating which of 140 species of this bacteria are responsible for the disease has remained elusive.

    The study’s principal investigators, Page Caufield, DDS, PhD, aprofessor of cariology and comprehensive care, and Yihong Li, DDS, a professor of basic science and craniofacial biology, will analyze several hundred bacteria samples from children with severe early childhood caries and their parents, and from caries-free children and their parents. Sampling and collection will take place at Bellevue Hospital Center in New York City.”

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Smoking

Chantix IS Unsuitable for First-Line Smoking Cessation

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According to a new study.

The poor safety profile of the smoking-cessation drug varenicline (Chantix™) makes it unsuitable for first-line use, according to a study published in the Nov. 2 edition of the journal PLoS ONE, an online publication of the Public Library of Science.

Varenicline, which already carries a “black box warning” from the U.S. Food and Drug Administration (FDA), showed a substantially increased risk of reported depression or suicidal behavior compared to other smoking-cessation treatments, according to researchers at Wake Forest Baptist Medical Center, the Institute for Safe Medication Practices, Harvard Medical School and Johns Hopkins University School of Medicine.

The researchers found that 90 percent of all reported suicides related to smoking- cessation drugs since 1998 implicated varenicline, even though it was on the market only four years in the nearly 13-year study period. They also found that varenicline was eight times more likely to result in a reported case of suicidal behavior or depression than nicotine replacement products.

The drug looked promising, I suppose. I had some friends who were heavy smokers and they reported the weird feelings and dreams as a result of taking Chantix.

They soon abandoned the program and returned to smoking.

Nicotine is a nasty, highly addictive drug and the best course of treatment is probably not to start in the first place.

“While suicidal behavior or depression appear to be prominent side effects of varenicline, they are by no means the only safety issues,” said Thomas J. Moore, senior scientist at the Institute for Safe Medication Practices and lead author of the study. “Varenicline has been associated with aggression and violence in three studies and carries a warning about this behavior. Its effects on vision, cognition and motor control and other risks have led to its being banned for airline pilots, air traffic controllers, military pilots and missile crews, and restricted for truck drivers.”

Varenicline also is associated with an increase in the risk of serious cardiovascular events, as reported in the July 4, 2011, issue of the Canadian Medical Association Journal by Furberg and scientists at Wake Forest Baptist, Johns Hopkins University School of Medicine and the University of East Anglia in the United Kingdom.

“We strongly recommend that the FDA should revise the ‘black box warning’ to say what this study and the FDA’s own data show — that varenicline has higher risks for suicidal behavior and depression than other smoking-cessation treatments,” Furberg said.

“We agree with the recommendations of the U.S. Veterans Administration (VA) that varenicline should be prescribed only after failure of nicotine replacement, bupropion or a combination,” he added. “The VA also recommends a mental status examination to assess risk of suicidal or violent behavior prior to prescribing varenicline.”

Tobacco use is responsible for one in five deaths in the United States each year and adds $193 billion to health care costs. It is among the most treatment-resistant forms of drug dependency, with 36 percent of the nation’s smokers attempting to quit each year but only 3 percent succeeding for six months or more, according to the Department of Health and Human Services.

Here is a video of some of the problems with Chantix:

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